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Clinical Data

Proven Clinical Effects

Clinical data shows that Otovent autoinflation treatment is an effective glue ear treatment that can reduce the need for surgical intervention. Where compliance with the treatment is high, data also shows that Otovent increases the chances of a shorter recovery time from glue ear.

Otovent clinical data


The latest clinical trial by Southampton University conducted on 320 children aged 4 to 11 years (Williamson et al. 2015) found that children using Otovent experienced fewer days with any glue ear related symptoms compared to those that didn’t at both one and three months.

 ‘We have found use of auto inflation in young, school-aged children with Otitis Media with Effusion to be feasible, safe and effective in clearing effusions, and in improving important ear symptoms, concerns and related quality of life over a 3-month watch-and-wait period. We are confident in our results and it looks like a very good method for improving symptoms and quality of life while reducing harmful treatments. It should be more widely used now." - Dr Ian Williamson

Reference:  Williamson I, Vennik J, Harnden A, Voysey M, Perera R, Kelly S, Yao G, Raftery J, Mant D, Little P. Effect of nasal balloon autoinflation in children with otitis media with effusion in primary care: an open randomized controlled trial. CMAJ, July 2015 DOI: 10.1503/cmaj.141608.

download pdf document about clinical trial on Otovent Effect of nasal balloon autoinflation in children with otitis media with effusion in primary care: an open randomized controlled trial

Watch how Jane Vennik, Research Fellow in Primary Care at the University of Southampton, demonstrates the nasal balloon autoinflation technique. In a pragmatic randomized control trial published in CMAJ, Jane Vennik, Dr. Ian Williamson, and colleagues found that nasal balloon autoinflation is a feasible, safe and effective treatment that should be used more often: 

There are a number of other studies on autoinflation. Some of them have been listed below:

download pdf document about clinical trial on Otovent Autoinflation as a Treatment of Secretory Otitis Media (pdf, 5mb)

download pdf document about clinical trial on Otovent Conservative treatment of otitis media with effusion by autoinflation of the middle ear (pdf,852kb)

download pdf document about clinical trial on Otovent Point Prevalence of Barotitis and its Prevention and Treatment with Nasal Balloon Inflation: A Prospective, Controlled Study (pdf, 163kb)

download pdf document about clinical trial on Otovent NHS Quick Reference Guide: Surgical Management of OME in Children February 2008 (pdf, 411kb)

download pdf document about clinical trial on Otovent NICE Guidelimes: Surgical Management of OME in Children February 2008 [FULL GUIDE] (pdf, 411kb)

As pointed out in the the 'NHS Quick Reference Guide: Surgical Management of OME in Children' document, NICE reommcends GPs should offer autoinflation during the active observation period to children with OME who are likely to cooperate. Those are usually children over 4 years-old as they must be able to inflate the Otovent balloon. 

Autoinflation is defined by NICE as 'a technique to open the Eustachian tube by raising the pressure in the nose, which allows air to enter the middle ear cavity.'  

A high-quality systematic review by Perera (2006) evaluated the effects of autoinflation in children with OME by comparing any form of autoinflation with no autoinflation. RCTs with other type of treatments (such as analgesia, decongestants or antibiotics) were included provided these were provided equally to the two groups. The population comprised children and adults with unilateral and bilateral OME and a clinical diagnosis by primary care physicians or specialists using tympanometry (type B or C2), either alone or in combination with simple or pneumatic otoscopy or audiometry. 

Primary outcomes measured were improvement in tympanogram, differences in hearing level on PTA and a composite improvement measured by change in either tympanogram or audiometry.

Source: Perera R. Autoinflation for hearing loss associated with otitis media with effusion. (Cochrane Review). In: Cochrane Database of Systematic Reviews, Issue 4, 2006. Chichester: Wiley Interscience.


Why choose to prescribe Otovent?

  • Reduce antibiotic prescriptions
  • Relieve symptoms of glue ear
  • Improve patient quality of life
  • Reduce referrals for audiology
  • Reduce the need for grommet surgery
  • Relieve Eustachian tube dysfunction (ETD)
  • Suitable for adults and children from 3 years of age

Available on prescription since 2001.

Prescription price: £4.90


Otovent is distributed by:

Kestrel Medical Ltd

7 Moor Road,


Dorset BH18 8AZ,


Tel: 01202 658 444


Did you know?

It is recommended to try using autoinflation with Otovent during the ‘watchful waiting’ period


NICE Guidelines

Download The Full Guide

Download the Quick Reference Guide  




Buy Online

Otovent is available online, on prescription from your GP and over the counter from your pharmacist.

  • Safe and natural
  • Non-invasive 
  • Clinically effective 


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